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Science17.04.2026

AI in Cardiology: Oxford Algorithm Predicts Heart Failure 5 Years Before Diagnosis

To achieve high predictive reliability, the model underwent comprehensive training on a database of CT scans and medical records."

A group of researchers from the University of Oxford has achieved a breakthrough in preventive cardiology by developing an artificial intelligence system for ultra-early diagnosis. The technology’s uniqueness lies in its ability to recognize hidden disease markers five years before a patient experiences the first clinical symptoms.

Analysis Technology: What CT Scans Hide

The method is based on deep analysis of cardiac CT scans. Scientists discovered that key clues about future health are hidden in changes within the fat tissue surrounding the heart. The artificial intelligence detects the slightest signs of inflammation, which remain completely invisible to the human eye, even upon the most careful examination by an experienced physician.

Training on Data from 70,000 Patients

To achieve high predictive reliability, the model underwent comprehensive training on a dataset covering more than 70,000 patients. The algorithm meticulously correlated structural changes in tissues with the subsequent development of pathologies over several years. Through this approach, the system learned not only to identify current anomalies but also to mathematically calculate the risk of heart failure in individuals who do not currently have an official diagnosis.

86% Accuracy and New Opportunities for Medicine

At the current stage, the neural network’s predictive accuracy has reached an impressive 86%. Such an early window for medical intervention provides doctors with an unprecedented opportunity to prescribe preventive therapy in a timely manner and prevent irreversible changes in heart function.

The Shift Toward Preventive Healthcare

This discovery could significantly reduce the burden on the healthcare system and, more importantly, save thousands of lives by shifting from treating consequences to preventing the disease itself. The use of AI in cardiology opens an era of personalized forecasting, where a diagnosis is made long before the first chest pain occurs.